Human Studies


Human Studies

261.Aoki, K., et al., Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Medical Gas Research, 2012. 2(1): p. 12.

262.Bittner, A.C., et al., Intra-Individual Ergonomics (I2E): Performance Effects of Ultra-Negative-Ion Water. Proceedings of the Human Factors and Ergonomics Society Annual Meeting SAGE Journals, 2007. 55(26): p. 1617-1621.

263.Drid, P., et al., Hydrogen-Rich Water in Judo Training. . Psycho-Physiological, Spiritual and Ethical Aspects), 2013: p. 129.

264.Fujiyama, Y. and T. Kitahora, Alkaline electrolytic water (alkali ions water) for drinking water in medicine. Mizu no Tokusei to Atarashii Riyo Gijutsu, Enu-Ti-Esu, Tokyo, 2004: p. 348-457.

265.Hiraoka, A., et al., Effects of drinking a water product with anti-oxidant activities in vitro on the blood levels of biomarker substances for the oxidative stress. Journal of Health Science, 2006. 52(6): p. 817-820.

266.Huang, K.C., et al., Electrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis. Nephrology Dialysis Transplantation, 2010. 25(8): p. 2730-2737.

267.Huang, K.C., et al., Electrolyzed-reduced water reduced hemodialysis-induced erythrocyte impairment in end-stage renal disease patients. Kidney Int, 2006. 70(2): p. 391-8.

268.Huang, K.C., et al., Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water. Kidney Int, 2003. 64(2): p. 704-14.

269.Ishibashi, T., et al., Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Medical Gas Research, 2012. 2(1): p. 27.

270.Ishibashi, T., et al., Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: A randomized, double-blind, placebo-controlled pilot study. Int Immunopharmacol, 2014. 21(2): p. 468-473.

271.Ito, M., et al., Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies. Medical Gas Research, 2011. 1(1): p. 24.

272.Kajiyama, S., et al., Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutrition Research, 2008. 28: p. 137–143.

273.Kang, K.-M., et al., Effects of drinking hydrogen-rich water on the quality of life of patients treated with radiotherapy for liver tumors. Medical Gas Research, 2011. 1: p. 11.

274.Koyama K, T.Y., Saihara Y, Ando D, Goto Y, Katayama A, Effect of hydrogen saturated alkaline electrolyzed water on urinary oxidative stress markers after an acute exercise: A randomized controlled trial. Anti-aging Med, 2008. 4: p. 117-122.

275.Lee, K.J., et al., Effect of electrolyzed-reduced water: in vivo and in vitro examination and clinical trials, in The 3rd Asia Pacific Conference on Evidence-Based Medicine. 2004: Hong Kong.

276.Li, Q., et al., Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro. Med Gas Res, 2013. 3(1): p. 20.

277.Lu, K.C., et al., Electrolyzed reduced water attenuates hemodialysis-induced mononuclear cells apoptosis in end-stage renal disease patients. Nephrology Dialysis Transplantation, 2006. 21: p. 200-201.

278.Matsumoto, S., T. Ueda, and H. Kakizaki, Effect of supplementation with hydrogen-rich water in patients with interstitial cystitis/painful bladder syndrome. Urology, 2013. 81(2): p. 226-30.

279.Nagatani, K., et al., Safety of intravenous administration of hydrogen-enriched fluid in patients with acute cerebral ischemia: initial clinical studies. Med Gas Res, 2013. 3: p. 13.

280.Nakao, A., et al., Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome-An Open Label Pilot Study. Journal of Clinical Biochemistry and Nutrition, 2010. 46(2): p. 140-149.

281.Nakayama, M., et al., Biological Effects of Electrolyzed Water in Hemodialysis. Nephron Clinical Practice, 2009. 112(1): p. C9-C15.

282.Nakayama, M., et al., A novel bioactive haemodialysis system using dissolved dihydrogen (H-2) produced by water electrolysis: a clinical trial. Nephrology Dialysis Transplantation, 2010. 25(9): p. 3026-3033.

283.Ono, H., et al., A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level. Medical Gas Research, 2012. 2(1): p. 21.

284.Ono, H., et al., Hydrogen(H2) treatment for acute erythymatous skin diseases. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers. Medical Gas Research, 2012. 2(1): p. 14.

285.Ostojic, S.M., Molecular Hydrogen in Sports Medicine: New Therapeutic Perspectives. Int J Sports Med, 2014. (human)

286.Ostojic, S.M. and M.D. Stojanovic, Hydrogen-rich water affected blood alkalinity in physically active men. Res Sports Med, 2014. 22(1): p. 49-60.

287.Ostojić, S.M., et al., Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women: Double-blind, randomized, placebo-controlled, cross-over trial of efficacy and safety. Serbian journal of sports sciences, 2011. 5(1-4): p. 83-89.

288.Ostojic, S.M., et al., Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. Postgrad Med, 2014. 126(5): p. 187-95.

289.Shin, M.H., et al., Atomic Hydrogen Surrounded by Water Molecules, H(H2O)m, Modulates Basal and UV-Induced Gene Expressions in Human Skin In Vivo. PLoS One, 2013. 8(4): p. e61696.

290.Song, G., et al., Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome. Journal of Lipid Research, 2013. 54(7): p. 1884-93.

291.Takeuchi, S., et al., Effects of intravenous infusion of hydrogen-rich fluid combined with intra-cisternal infusion of magnesium sulfate in severe aneurysmal subarachnoid hemorrhage: study protocol for a randomized controlled trial. BMC Neurol, 2014. 14(1): p. 176.

292.Tashiro, H., et al., Clinical evaluation of alkali-ionized water for chronic diarrhea-placebo-controlled double blind study. Digestion & Absorption, 2000. 23: p. 52-56.

293.Terawaki, H., et al., Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity. Medical Gas Research, 2013. 3(1): p. 14.

294.Xia, C., et al., Effect of hydrogen-rich water on oxidative stress, liver function, and viral load in patients with chronic hepatitis B. Clin Transl Sci, 2013. 6(5): p. 372-5.

295.Yang, E.J., et al., A Clinical Trial of Orally Administered Alkaline Reduced Water. 대한의생명과학회지, 2007. 13(2): p. 83-89.

296.Yeung, L.K., et al., Effect of electrolyzed reduced water hemodialysis on peripheral lymphocyte intracellular cytokine expression. Nephrology Dialysis Transplantation, 2006. 21: p. 204-204.

297.Yoritaka, A., et al., Pilot study of H(2) therapy in Parkinson’s disease: A randomized double-blind placebo-controlled trial. Movement Disorders, 2013.