Search Results for: cytotoxic reactive oxygen species

DR. WILLIAM ALLEN BANKS

“In our published study in PLoS One, hydrogen water was remarkable in reversing the various changes induced by controlled cortical impact, an experimental model of traumatic brain injury.” EDUCATION 1972 Graduated, Bloomfield High School, Bloomfield, MO1975 B.A., University of Missouri-St. Louis, Magna Cum Laude in Biology1979 M.D., University of Missouri-Columbia. TRAINING AND APPOINTMENTS LICENSES AND BOARD CERTIFICATIONS (Board…

DR. MAMI NODA, PHD

DR. MAMI NODA, PHD

“I have been involved with pharmacology for over 30 years. After my postdoctoral fellow at the Rockefeller University, I continued my research at Kyushu University, where “alkaline ionized water” was initially studied in 1997. Although there was a significant amount of false information contained in the marketing, and it became quite popular in Japan, I…

DR. JIANGANG LONG, PHD. (XI’AN JIAOTONG UNIVERSITY)

DR. JIANGANG LONG, PHD. (XI’AN JIAOTONG UNIVERSITY)

Mitochondrion is the key organelle for cellular ATP supply and apoptosis signaling. We are engaged in exploring mitochondrial metabolism under physiological and pathological conditions, and pursuing the mitochondrion-targeted molecules to improve mitochondrial function and maintain mitochondrial homeostasis damaged during neurodegeneration and nutritional imbalance.Since the discovery of the antioxidant effect of H2 in 2007, we recently identified…

Free Radicals: The Positive & Negative Effects On Health

Free Radicals: The Positive & Negative Effects On Health

ROS PRODUCTION Reactive oxygen species (ROS) are biological products of metabolism that exert both positive and negative effects on the body.  ROS include free radicals like the hydroxyl radical (OH·), superoxide anion radical (O2–), nitric oxide (NO·), etc.1 as well as other oxidants  (e.g. hydrogen peroxide (H2O2), peroxynitrite (ONOO-) singlet oxygen (1O2), etc.).2 The primary source of ROS formation…

Miscellaneous

Miscellaneous

Zhang, W., et al., Hydrogen alleviates cellular senescence via regulation of ROS/p53/p21 pathway in bone marrow-derived mesenchymal stem cells in vivo. Biomedicine & Pharmacotherapy, 2018. 106: p. 1126-1134. Xu, F., et al., Hydrogen-Rich Saline Ameliorates Allergic Rhinitis by Reversing the Imbalance of Th1/Th2 and Up-Regulation of CD4+CD25+Foxp3+Regulatory T Cells, Interleukin-10, and Membrane-Bound Transforming Growth Factor-beta in Guinea…

Hydrogen: An Emerging Medical Gas

Hydrogen: An Emerging Medical Gas

INTRODUCTION Molecular hydrogen (i.e. H2 gas) is gaining significant attention from academic researchers, medical doctors, and physicians around the world for its recently reported therapeutic potential [1]. One of the earliest publications on hydrogen as a medical gas was in 1975, by Dole and colleagues from Baylor University and Texas A&M [2]. They reported in the journal Science that…

Hydroxide (OH–): Antioxidant? Radical? Or Neither

Hydroxide (OH–): Antioxidant? Radical? Or Neither

HYDROXIDE (OH–) CONFUSION There appears to be a lot of confusion about the hydroxide ion, i.e. OH–, (also incorrectly called just “hydroxyl”, which ironically is a free radical or even “hydroxyl water”) within the “ionized water community”. This is because numerous websites, marketers, sales pitches, explanations, etc. claim that hydroxides are antioxidants. 1,2  Recently, however, there are…

Free Radicals: The Positive & Negative Effects On Health

Free Radicals: The Positive & Negative Effects On Health

ROS PRODUCTION Reactive oxygen species (ROS) are biological products of metabolism that exert both positive and negative effects on the body.  ROS include free radicals like the hydroxyl radical (OH·), superoxide anion radical (O2–), nitric oxide (NO·), etc.1 as well as other oxidants  (e.g. hydrogen peroxide (H2O2), peroxynitrite (ONOO-) singlet oxygen (1O2), etc.).2 The primary source of ROS formation…